Ensaios Clínicos

Promotor Serviço Investigador Principal Ensaio
ABBVIE REUMATOLOGIA Dr.ª Cláudia Vaz M16-852 – A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Giant Cell Arteritis.
MEDICINA INTERNA
SANOFI PNEUMOLOGIA Dr. José Manuel Silva AERIFY – Randomized, doub -blind, placebo-controlled, parallelgroup Phase 3 study to evaluate the efficacy, safety, and tolerability of SAR440340/REGN3500/itepekimab (anti-IL-33 mAb) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD).
NOVO NORDISK MEDICINA INTERNA Dr. Adriano Cardoso ESSENCE – The effect of semaglutide in subjects with non-cirrhotic non-alcoholic steatohepatitis
POLYPID CIRURGIA Prof. Doutor Augusto Lourenço D-PLEX / SHIELD II– Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two‐arm, Double Blind Study to Assess Efficacy and Safety of D‐PLEX Administered Concomitantly with the Standard of Care (SoC), Compared to a SoC Treated Control Arm, in Prevention of Post Abdominal Surgery Incisional Infection.
GSK PNEUMOLOGIA Dr. José Manuel Silva NIMBLE – A 52-week, Randomized, double-blind, double-dummy, parallel group, multi-centre, non-inferiority study assessing exacerbation rate, additional measures of asthma control and safety in adult and adolescent severe asthmatic participants with an eosinophilic phenotype treated with GSK3511294 compared with mepolizumab or benralizumab.
SEAGEN ONCOLOGIA Dr.ª Inês Sequeira MOUNTAINEER– An Open-label Randomized Phase 3 Study of Tucatinib in Combination with Trastuzamab and mFOLFOX6 given with or without either Cetuximab or Bevacizumab as First-line Treatment for Subjects with HER2+ Metastatic Colorectal Cancer.
NOVARTIS REUMATOLOGIA Dr.ª Cláudia Vaz NEPTUNUS-E1: A randomized, double-blind 2-arm NEPTUNUS extension study to assess the long-term safety and efficacy of ianalumab in patients with Sjögren’s syndrome (CVAY736A2301E1).
JANSSEN REUMATOLOGIA Dr.ª Cláudia Vaz STAR: A Phase 4, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Guselkumab Administered Subcutaneously in Bio-naive Participants with Active Psoriatic Arthritis Axial Disease.
IDORSIA REUMATOLOGIA Dr.ª Cláudia Vaz OPUS: A Phase 3, multicenter, randomized, double-blind, placebo-controlled,parallel-group study to evaluate the efficacy, safety, and tolerability of cenerimod in adult subjects with moderate-to-severe systemic lupus erythematosus (SLE) on top of background therapy.
VEDANTA MEDICINA INTERNA (INFECCIOLOGIA) Dr.ª Catarina Quinaz RESTORATIVE: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of VE303 for Prevention of Recurrent Clostridioides difficile Infection (RestoratiVE303)
SOLFARCOS REUMATOLOGIA Dr.ª Cláudia Vaz FBL-MTX-201: Phase IIa Proof-of-Concept Study, with Dose-Titration Based on Treat-to-Target Strategy, to Investigate the Efficacy, Safety, and Tolerability of Subcutaneous Injection of Folate-based Liposomes Encapsulating Methotrexate (FBL-MTX) in Disease-modifying Antirheumatic Drugs (DMARD)-naïve Patients with Moderate-to-Severe Active Rheumatoid Arthritis and in Patients with an Inadequate Response or Intolerance to Oral MTX.

 

Estudos Observacionais:

Promotor Serviço Investigador Principal Ensaio
ROS PSIQUIATRIA Dr.ª Sílvia Castro RESHAPE: Risperidone ISM® Effectiveness in Schizophrenia patients Hospitalised due to A relapse: a Prospective noninterventional Evaluation (RESHAPE study)
EVIDENZE CUIDADOS DE SAÚDE PRIMÁRIOS Dr.ª Ana Catarina Monteiro SNAPSHOT: Multi-National Cross-Sectional Epidemiological Study of Hypertensive Patients with Dyspilipidemia and Patient Reported Outcomes.